Lifespan: Why We Age—and Why We Don't Have To

Discover the science that will let you stay young for decades

David A. Sinclair

2019

8 Key Insights

About This Book

Imagine a life where fatigue, pain and disease don’t define your later years. In Lifespan, pioneering scientist David Sinclair unveils a bold new vision: aging is not a fixed fate but a treatable condition. Drawing on breakthroughs in genetics, epigenetics and cellular reprogramming, Sinclair shows how simple lifestyle tweaks and emerging therapies—fasting, cold exposure, NAD boosters, precision medicine and even gene therapy—can keep your body resilient and your mind sharp for decades longer. Packed with powerful case studies and practical guidance, Lifespan equips you to seize control of your biology and live healthier, more vibrant years.

About the Author

David Sinclair is a Harvard Medical School professor and codirector of the Paul F. Glenn Center for the Biological Mechanisms of Aging. A leader in longevity research for over thirty years, he has published hundreds of peer-reviewed papers, co-founded biotech companies and advised governments worldwide on aging science. His work has earned him numerous awards, including Australia’s equivalent of a knighthood, and his dynamic public speaking makes complex science accessible. Sinclair lives in Boston with his wife and children, whom he inspires with his passion for lifelong curiosity.

Biggest Takeaway

• Reframe aging as a treatable process, not an inevitable decline. • Harness your own survival genes through fasting, exercise, temperature stress and natural compounds. • Learn how NAD precursors and sirtuin activators can rejuvenate cells and extend healthy lifespan. • Discover cutting-edge therapies—senolytics, precision genomics and cellular reprogramming—to prevent age-related diseases. • Gain clear, actionable steps to maintain peak physical and cognitive performance deep into your later decades.

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